A. Okten et al., Renal duplex Doppler ultrasonography as a predictor of preclinical diabetic nephropathy in children, ACT RADIOL, 40(3), 1999, pp. 246-249
Purpose: To perform Doppler US in patients with insulin-dependent diabetes
mellitus (IDDM) as a predictive method in diabetic nephropathy (DN).
Material and Methods. Twenty-five patients with type I diabetes mellitus un
derwent renal Doppler US examination. Children were divided into three age
groups: group I, 3-7 years; group II? 8-10 years; and group III, 11-18 year
s. The age-matched control group consisted of 56 healthy children who under
went renal Doppler US only.
Results. The mean values of the resistive index (RI) were, respectively, 0.
64+/-0.03, 0.59+/-0.04, 0.59+/-0.02 in age groups I, II, and III for health
y children and 0.68+/-0.03, 0.62+/-0.04, 0.59+/-0.04 in age groups I, II, a
nd III of the diabetic patients. There were no significant differences betw
een the diabetic and healthy subjects. The mean RI value was not different
in the patients with glomerular hyperfiltration compared to patients with n
ormal filtration rate. Additionally, there were no significant differences
between the mean RI value in patients with or without microalbuminuria.
Conclusion. Renal Doppler US is not useful for prediction or for early diag
nosis of DN.