U. Anand et al., Intradialytic dobutamine therapy in maintenance hemodialysis patients withpersistent hypotension, AM J NEPHR, 19(4), 1999, pp. 459-463
Intradialysis hypotension is a common problem, especially in patients with
poor left-ventricular function. We studied 6 patients who were on maintenan
ce hemodialysis with left-ventricular ejection fraction of <40%, whose dial
ysis sessions were often complicated with severe hypotension (systolic bloo
d presure <90 mm Hg). Dobutamine infusion during dialysis significantly red
uced the number of hypotensive episodes, increased left-ventricular ejectio
n fraction, and decreased the number of emergency admissions to the hospita
l.