Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds

Citation
Af. Barrero et al., Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds, BIOORG MED, 9(16), 1999, pp. 2325-2328
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
16
Year of publication
1999
Pages
2325 - 2328
Database
ISI
SICI code
0960-894X(19990816)9:16<2325:SAAAOM>2.0.ZU;2-6
Abstract
Efficient syntheses of ent-isozonarol (6a), ent-isozonarone (7a) and ent-ch romazonarol (8) from (-)-sclareol (12) are described. 6a and 7a show a sign ificative antitumoral activity. (C) 1999 Elsevier Science Ltd. All rights r eserved.