Jx. Yu et al., Synthesis of 3-alkyl/aryl-6-(1 '-N-beta-D or alpha-L-acetylated glycopyranosyl)-s-triazolo[3,4-b]-1,3,4-thiadiazoles, CHEM J CH U, 20(8), 1999, pp. 1233-1237
3-Alkyl/aryl-4-amino-5-mercapro-1,2,4-triazoles(5)were condensed with 2,3,4
,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate(3) or 2,3, 4-tri-O-a
cetyl-alpha-L-rhamnopyranosyl isothiocyanate(4) in anhydrous EtOH under ref
lux to afford 14 novel 3-alkyl/aryl-6- (1'-N-2', 3',4',6'-tetra-O-acetyl-be
ta-D-glucopyranosyl or 1'-N-2', 3', 4'-tri-O-acetyl-alpha-L-rhamnopyranosyl
)-s-triazolo [3,4-b]-1,3,4-thiadiazoles (6a-6i, 7a-7e). Their structures we
re confirmed by elemental analysis, IR and H-1 NMR spectral data.