Serum protein binding of desmethyl-methsuximide

Authors
Wad, N Bourgeois, B Kramer, G
Citation
N. Wad et al., Serum protein binding of desmethyl-methsuximide, CLIN NEUROP, 22(4), 1999, pp. 239-240
Citations number
3
Categorie Soggetti
Neurosciences & Behavoir
Journal title
CLINICAL NEUROPHARMACOLOGY
ISSN journal
03625664 → ACNP
Volume
22
Issue
4
Year of publication
1999
Pages
239 - 240
Database
ISI
SICI code
0362-5664(199907/08)22:4<239:SPBOD>2.0.ZU;2-E
Abstract
Serum protein binding of desmethyl-methsuximide (DM-MSM) in serum from 23 p atients on polytherapy were determined using ultrafiltration and highperfor mance liquid chromatography. Desmethyl-methsuximide, The active metabolite of methsuximide (MSM), was found to have a moderate protein binding ranging between 45% and 60%.