Magnetic resonance imaging in a hands-on student experiment using an EPR spectrometer

Many modern medical diagnostic techniques, including magnetic resonance ima ging (MRI) and computed tomography, are based on image reconstruction from projections. Unfortunately, the high cost of acquiring, maintaining, and op erating MRI equipment makes it unavailable for hands-on undergraduate stude nt laboratory experiments. Here, we describe a laboratory module for teachi ng the principles of MRI. It is based on a minor modification of an ordinar y continuous wave electron paramagnetic resonance spectrometer. By applying magnetic held gradients, students learn the basic principles of MRI and pr actice with samples made from stable free radicals and a roasted coffee bea n. The value of this laboratory experiment is to connect magnetic resonance spectroscopy with its application in imaging and to provide students with hands-on experience in the basics of computer-assisted tomography. (C) 1999 John Wiley & Sons, Inc.