Cloacogenic adenocarcinoma of the vulva

Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterize d by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin h istochemistry of enteric adenocarcinoma. Electron microscopy verified a col on-like pattern. We suggest that cloacogenic carcinoma of the vulva arises from embryonic tissue, normally present in the vulvar introital area. In ou r case, a wide local excision was sufficient for radical cure, (C) 1999 Aca demic Press.