We present here a case of primary leiomyosarcoma of the greater omentum in
a 15-year-old girl. A laparotomy revealed a huge abdominal mass arising fro
m the greater omentum. The tumor accompanied intra-abdominal dissemination,
but had not invaded the muscle layer of the gastrointestinal tracts. An al
most complete omentectomy and reduction of many disseminated tumors of abdo
minal wall and mesentery were performed for the case. The tumor was diagnos
ed as a leiomyoscarcoma by histological and immunohistochemical examination
s. After the surgery, combination chemotherapy with cisplatin, ifosfamide,
and pirarubicin was carried out. Leiomyosarcoma of the greater omentum in a
young girl is extremely rare. (C) 1999 Academic Press.