Two new quinazoline-quinoline alkaloids, luotonins E (1) and F (2), were is
olated from the aerial parts of Peganum nigellastrum along with two known a
lkaloids 3-quinolinecarboxamide (3) and pegamine (4). The structures of luo
tonins E and F were determined to be the formulae(1) and(2), respectively,
by spectroscopic and synthetic methods.