4-Aminobenzophenone 1 on condensation with different araldehydes yield schi
ffs bases 2a-o which on cyclization with mercapto acetic acid afford the co
rresponding 4-(5'H-2'aryl-4'-thiazolidinon-3'-yl)-benzophenones 3a-o. While
cyclocandensation of 1 with various azlactones yield 4-(4'-arylidene-2'-ph
enyl-5'-oxa-imidazolin-1'-yl)benzophenones 4a-m. The structure of the compo
unds have been confirmed from elemental analysis, IR, H-1 NMR and mass spec
tral data. All the compounds have been evaluated in vitro for antimicrobial
and antimycobacterial activities.