A new compound 27-methylnonaeicosanol 1 together with known lipids, triterp
enoids, flavonoids, bioactive andrographolide and neoandrographolide have b
een isolated from Holmskioldia sanguinea and identified by their spectral a
nd chemical study. This is the second natural occurrence of andrographolide
and neoandrographolide, and their first occurrence from H. sanguinea is of
chemotaxonomic importance.