The larvicidal activity of seed and leaf extracts of Calophyllum inophyllum
and leaf extract of Rhinacanthus nasutus on the juveniles of Culex quinque
fasciatus, Anopheles stephensi and Aedes aegypti was determined. Ethyl acet
ate (EA) soluble fractions of C. inophyllum and petroleum ether (PE) fracti
on of R. nasutus extracts showed very high larvicidal activity. Irrespectiv
e of the species of the mosquitoes tested, at concentrations ranging from 3
.91 to 9.39 ppm, 9.04 to 35.49 ppm and 13.21 to 28.92 ppm of the active fra
ctions of seed and leaf extracts of C. inophyllum and the leaf extract of R
. nasutus, respectively, killed 50% of the treated larvae. The fractions al
so interfered with adult emergence. Exposure of the mosquitoes at any stage
of their larval development to less than 0.86, 5.49 and 6.81 ppm of the ac
tive fractions of seed and leaf extracts of C. inophyllum and the leaf extr
act of R. nasutus, respectively, inhibited 50% of the treated larvae from e
merging as adults. Experiments under laboratory and semi-field conditions s
howed that the activity of the extracts persisted for up to 10 days.