There have been only a few reports that evaluate the outcome of total knee
arthroplasty in patients with steroid-induced osteonecrosis of the knee. We
retrospectively reviewed 31 total knee arthroplasties in 24 patients with
confirmed steroid induced osteonecrosis of the knee. The average follow-up
was 64 months. Of surviving knees, 92% had significant improvement in knee
scores. Five knees (16%) required a revision procedure. Reasons for revisio
n were aseptic loosening in 3 knees and sepsis in 2 knees. Complications no
t requiring revision occurred in 6 of 31 knees (19%). Survivorship of total
knee arthroplasty to revision in patients with steroid-induced avascular n
ecrosis of the knee was 84% at 5 years. Although there was a slightly highe
r complication rate, this may, in part, be due to the severity of the patie
nts' underlying disease processes. Total knee arthroplasty can be a success
ful procedure for chronically ill patients with steroid-induced osteonecros
is.