SYNTHESIS OF 2',3'-DIDEOXY-2'-HYDROXYMETH YL NUCLEOSIDES

Authors
NOE CR BUCHSTALLER HP HABERHAUER G HOLZNER A
Citation
Cr. Noe et al., SYNTHESIS OF 2',3'-DIDEOXY-2'-HYDROXYMETH YL NUCLEOSIDES, Monatshefte fuer Chemie, 128(5), 1997, pp. 509-527
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
128
Issue
5
Year of publication
1997
Pages
509 - 527
Database
ISI
SICI code
0026-9247(1997)128:5<509:SO2YN>2.0.ZU;2-0
Abstract
The synthesis of protected 2',3'-dideoxy-2'-hydroxymethyl nucleosides is presented. The nucleo sides, obtained in a multi-step procedure sta rting from isopropylideneglycerol, may be used as building blocks for the synthesis of 2',5'-ether linked oligonucleotides.