Detection of Chlamydia trachomatis endocervical infections by ligase chainreaction versus ACCESS Chlamydia antigen assay

Citation
Kb. Waites et al., Detection of Chlamydia trachomatis endocervical infections by ligase chainreaction versus ACCESS Chlamydia antigen assay, J CLIN MICR, 37(9), 1999, pp. 3072-3073
Citations number
7
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
37
Issue
9
Year of publication
1999
Pages
3072 - 3073
Database
ISI
SICI code
0095-1137(199909)37:9<3072:DOCTEI>2.0.ZU;2-I
Abstract
Ligase chain reaction (LCR) was compared with ACCESS immunoassay for detect ion of chlamydial infections in females. Despite efforts to improve ACCESS performance by evaluation of specimens that were in the test performance "g rey zone," LCR remained more sensitive and was less expensive to perform. A CCESS had a sensitivity of 83.9%, a specificity of 99.7%, a positive predic tive value of 96.3%, and a negative predictive value of 98.5%.