E. Chruscinska et al., L-Mimosine, an amino acid with maltol-type binding properties toward copper(II), oxovanadium(IV) and other metal ions, J INORG BIO, 75(3), 1999, pp. 225-232
The complex formation between L-mimosine, alpha-amino-beta-(3-hydroxy-4-oxo
-1,4-dihydropyridin-1-yl)-propanoic acid, a rare a-amino acid provided with
a 3-hydroxypyridin-4(1H) one moiety, and some metal ions - Cu(II), VO(IV),
Ni(II) and Zn(II) - was studied by spectroscopic (EPR and electron absorpt
ion) and potentiometric techniques in aqueous solution. It was found that L
-mimosine prefers the maltol-like donor set of the 3-hydroxypyridin-4 (IH)o
ne fragment for binding copper(II) and oxovanadium(IV). However, the presen
ce of two alternative donor centres in the ligand, (COO-, NH,) and (CO, O-)
, both suitable for chelating behaviour, makes possible the formation of ve
ry stable polynuclear species in which the L-mimosine ligand coordinates at
both the (CO, O-) maltol-like and the (COO-, NH2) alpha-aminocarboxylate s
ites. Nickel(II) interacts with the ligand, but prefers a mixed bonding mod
e in the bis chelated species. Zn(II) only forms complexes with the 3-hydro
xypyridin-4(1H) one fragment. (C) 1999 Elsevier Science Inc. All rights res
erved.