SYNTHESIS AND CHARACTERIZATION OF COPPER(II) COMPLEXES OF ADENINE ANDAMINO-ACIDS

Complexes [Cu(CH3COO)(ade-H)(H2O)]H2O)(I), [Cu(CH3COO) (ade-H)(0.5 ade ) (0.5H(2)O)] 2H(2)O (Ia), [Cu(CH3COO)(ade-H)(ade)]2H(2)O] (Ib), [Cu(C lCH2COO)(ade-H) (H2O)] H2O (II), [(Cu(CNCH2COO)(ade-H)(H2O)] H2O (III) , where ade = adenine (C5H5N5), have been prepared. I, II and III on i nteraction with aminoacids such as glycine, alanine or glutamic acid g ive the complexes of the type [Cu(XCH2COO)(aa)(ade)(2H(2)O)], where X= H, Cl or CN and Haa = aminoacid, which are characterized by elemental and thermal analyses, electronic, infrared and EPR spectroscopic studi es and variable temperature magnetic susceptibility measurements. Simp le adeninato complexes are found to be dimeric, involving the bridging of the anionic adenine through the imidazole (N9) and the pyrimidine (N3) nitrogens and the acetato group through the carboxylate oxygens, while mixed adenine-aminoacidato complexes are monomeric, involving th e bonding of the N(7) of adenine, the oxygen of acetate and aminoacid, in addition to the coordination of water molecules.