Surveillance and laboratory confirmation of measles will increase in import
ance as Australia implements enhanced measles control. We describe a 17-mon
th-old child with fever and rash after measles-mumps-rubella vaccination. D
etection of vaccine-strain measles virus in his urine by polymerase chain r
eaction confirmed the diagnosis of a vaccine reaction rather than wildtype
measles. We propose that measles virus should be sought and identified as v
accine or wild-type virus when the relationship between vaccination and mea
sles-like illness is uncertain.