Citation
Au. Khan et Sk. Lal, Ribozymes: structure and potential applications in medicine, MED SCI RES, 27(8), 1999, pp. 507-512
Citations number
47
Categorie Soggetti
Medical Research General Topics
Journal title
MEDICAL SCIENCE RESEARCH
ISSN journal
02698951
→ ACNP
Volume
27
Issue
8
Year of publication
1999
Pages
507 - 512
Database
ISI
SICI code
0269-8951(199908)27:8<507:RSAPAI>2.0.ZU;2-3
Abstract
Ribozymes are a class of ribonucleic acid (RNA) molecules that possess enzy
matic properties. Upon binding to complementary nucleic acid strands, catal
ytic degradation occurs via a cleavage reaction. In effect, inactivation of
susceptible substrate RNA molecules take place at a catalytic rate and wit
h a high degree of substrate specificity. This review deals with the struct
ure, design and potential applications of ribozymes in medicine. Med Sci Re
s 27:507-512 (C) 1999 Lippincott Williams & Wilkins.