Assessing ocular drug delivery with lachrimal scintigraphy

In order to transmit well focused images to the retina, the eye must have c onstant dimensions and an unclouded optical pathway. These requirements dic tate that the eye has a well developed system to ensure consistent optics a nd that any material applied to the eye is rapidly cleaved. Unfortunately, this can severely limit the effectiveness of topically applied medication. This review outlines a key method by which ocular drug delivery can be asse ssed - lachrimal scintigraphy - in a non-invasive, physiologically relevant setting.