Electronic sputtering in the interaction of slow (v < 10(6) m/s), highly ch
arged ions (e.g., AU(69+)) With Solid surfaces increases secondary ion yiel
ds by over two orders of magnitude compared to sputtering with singly charg
ed ions. We discuss advantages of highly charged ions for analysis of semic
onductors and biomolecular solids in a time-of-flight secondary ion mass sp
ectrometry scheme.