A new amide of threo-gamma-hydroxyglutamic acid, justiciamide, was isolated
from Justicia ghiesbreghtiana and shown to be (-)-N-(2-hydroxy-4,5-dimetho
xyphenyl)-(2 S,4 S)-gamma-hydroxyglutamic acid. Justiciamide is the first a
mide of an uncommon amino acid found in this genus. (C) 1999 Elsevier Scien
ce Ltd. All rights reserved.