A highly practical route to 7-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one from p-anisidine

Authors
Wu, CD Biediger, RJ Kogan, TP
Citation
Cd. Wu et al., A highly practical route to 7-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one from p-anisidine, SYN COMMUN, 29(20), 1999, pp. 3509-3516
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
29
Issue
20
Year of publication
1999
Pages
3509 - 3516
Database
ISI
SICI code
0039-7911(1999)29:20<3509:AHPRT7>2.0.ZU;2-B
Abstract
The title compound was accessed via a Friedel-Crafts reaction on anisidine, followed by cyclization, N-methylation and O-demethylation, No column chro matography was required in the process.