Intramolecular hydrogen bonding and its influence on conformation. Circular dichroism of chiral bilirubin analogs

Authors
Boiadjiev, SE Lightner, DA
Citation
Se. Boiadjiev et Da. Lightner, Intramolecular hydrogen bonding and its influence on conformation. Circular dichroism of chiral bilirubin analogs, TETRAHEDR-A, 10(13), 1999, pp. 2535-2550
Citations number
36
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
13
Year of publication
1999
Pages
2535 - 2550
Database
ISI
SICI code
0957-4166(19990702)10:13<2535:IHBAII>2.0.ZU;2-W
Abstract
Enantiopure synthetic bilirubin analogs with variously modified (e.g. alkyl for natural propionic acid or ester) C(8) and C(12) side chains and with b ut a single chiral center in either or both, exhibited exciton coupled circ ular dichroism (CD) spectra. The CD intensity is greater when the stereogen ic center is in a propionic acid side chain than in an alkyl side chain. (C ) 1999 Elsevier Science Ltd. All rights reserved.