Cephalosporins - pharmacological basis of clinical use in veterinary dermatology

Cephalosporins form a large group of p-lactam antibiotics which are used ex tensively in human medicine and to a lesser extent in domestic animals. In veterinary dermatology, the principle use for the cephalosporins is the cli nical management of canine pyoderma associated with Staphylococcus intermed iate. In practice, the use of orally administered first generation cephalos porin drugs to affected dogs is well tolerated and highly efficacious. Bact erial drug resistance appears to occur rarely.