Sulphonamides: updates on use in veterinary medicine

Sulphonamides are the oldest class of antimicrobials and are still the drug of choice for many diseases in veterinary patients. They are classified ba sed on their pharmacokinetics and pharmacodynamics. This article presents a n overview of various sulphonamides in each classification, the mechanisms of bacterial resistance, and the effectiveness and maintenance of skin conc entrations. Clinical indications, routes and frequency of administration, d uration of therapy, compliance factors, cost, adverse drug reactions and dr ug interactions are described. Controversial topics such as current usage a nd recommendations for sulphonamide use in dermatology are also discussed.