The aim of this clinical study was to determine the tumour control rate, cl
inical outcome and complication rate following gamma knife treatment for gl
omus jugulare tumours. Between May 1992 and May 1998, 13 patients with glom
us tumours underwent stereotactic radiosurgical treatment in our department
. The age of these patients ranged from 21 to 80 years. The male : female r
atio was 2:11. Six patients had primary open surgery for partial removal or
recurrent growth and subsequent radiosurgical therapy. Radiosurgery was pe
rformed as primary treatment in 7 cases. The median tumour volume was 6,4cm
(3) (range: 4,6-13,7 cm(3)). The median marginal dose applied to an average
isodose volume of 50% (30-50%) was 13,5 Gy (12-20Gy). In 10 patients =, a
total of 48 MRI and CT follow-up scans were available. The remaining three
patients have been excluded from the postradiosurgical evaluation since the
observation time (t < 12 months) was too short or patients were lost to fo
llow up. The median interval from Gamma Knife treatment to the last radiolo
gical follow up was 37,6 months (5-68 months). In 4 patients (40%) decrease
d tumour volumes were observed and in 6 cases (60%) the tumour size remaine
d unchanged. Neurological follow-up examinations revealed improved clinical
status in 5 patients (50%) and no complications occurred. According to our
preliminary experience Gamma Knife radiosurgery represents an effective tr
eatment option for glomus jugulare tumours.