Impact of CT in patients with sepsis of unknown origin

Purpose: To evaluate the diagnostic relevance of CT in patients with sepsis of unknown origin. Material and Methods: Sixty-three consecutive intensive care patients with suspicion of an abscess and negative or inconclusive previous radiological examinations were included. CT was performed using the helical technique. A total of 45 abdominal and 38 chest examinations were evaluated. Results: 5/38 examinations of the chest revealed the source of sepsis (pleu ral empyema 2, lung abscess 1, mediastinitis 1, retrosternal abscess 1). 7/ 45 abdominal CT examinations showed the source of sepsis (intraabdominal ab scess 2, hepatic abscess 3, intestinal perforation 1, gangrenous colitis 1) . Conclusion: CT is useful for the evaluation of patients with fever or sepsi s without a known source. Due to the detection of a septic focus by CT, 19% of the patients in our study could be immediately referred to causal thera py as percutaneous drainage or surgery.