S. Fotiou et al., CLASS-III VS CLASS-II RADICAL HYSTERECTOMY IN STAGE IB CERVICAL-CARCINOMA - A COMPARISON OF MORBIDITY AND SURVIVAL, International journal of gynecological cancer, 7(2), 1997, pp. 117-121
The classical Fiver III and a modified class II radical hysterectomy w
ere applied in stage IB patients with cervical cancer and were compare
d as to morbidity and disease-free survival (DFS). Class III was perfo
rmed in a group of 68 cases and class II in 50. The mean observation p
eriod was 31 and 69 months respectively. Most of the prognostic factor
s (age, histology, grade, bulky tumors, lymph node (LN) metastases) we
re comparable in the two groups. Postoperative irradiation was given t
o 31% and 64% of the type III and II hysterectomy group respecitvely (
P<0.05). Perioperative morbidity (mean operative time, blood units tra
nsfused, febrile cases and hospital stay) was quite similar. Major com
plications (mainly voiding problems) were significantly more frequent
in class III operation. However, DFS was higher (86.5% vs 76.5%, P < 0
.05) after class III hysterectomy. These data indicate that class III
operation is a more morbid procedure but appears to be advantageous re
garding survival. In order to reduce morbidity without compromising th
erapeutic results (tailoring the radicality), a better insight in the
prognostic factors is necessary.