Synthesis and in vitro antibacterial activity of C-3 ' pyridinium cephalosporin derivatives

Citation
Ih. Chung et al., Synthesis and in vitro antibacterial activity of C-3 ' pyridinium cephalosporin derivatives, ARCH PH RES, 22(4), 1999, pp. 391-397
Citations number
15
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
22
Issue
4
Year of publication
1999
Pages
391 - 397
Database
ISI
SICI code
0253-6269(199908)22:4<391:SAIVAA>2.0.ZU;2-S
Abstract
The quaternary ammonium cephalosporin derivatives were prepared with variou s pyridines substituted at the 3 or/and 4 position. Their in vitro antibact erial activities were determined and substituent effect on pyridine nucleus was studied. Preparation of substituted pyridines are also described.