The potential use of non-invasive methods in the safety assessment of cosmetic products - The report and recommendations of an ECVAM/EEMCO workshop (ECVAM Workshop 36)

Citation
V. Rogiers et al., The potential use of non-invasive methods in the safety assessment of cosmetic products - The report and recommendations of an ECVAM/EEMCO workshop (ECVAM Workshop 36), ATLA-ALT L, 27(4), 1999, pp. 515-537
Citations number
150
Categorie Soggetti
Animal & Plant Sciences
Journal title
ATLA-ALTERNATIVES TO LABORATORY ANIMALS
ISSN journal
02611929 → ACNP
Volume
27
Issue
4
Year of publication
1999
Pages
515 - 537
Database
ISI
SICI code
0261-1929(199907/08)27:4<515:TPUONM>2.0.ZU;2-U
Abstract
This is the report of the thirty-sixth of a series of workshops organised b y the European Centre for the Validation of Alternative Methods (ECVAM). EC VAM's main goal, as defined in 1993 by its Scientific Advisory Committee, i s to promote the scientific and regulatory acceptance of alternative method s which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which w ould enable it to become better informed about the state-of-the-art of non- animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures. It was decid ed that this would be best achieved by the organisation of ECVAM workshops on specific topics, at which small groups of invited experts would review t he current status of various types of in vitro tests and their potential us es, and make recommendations about the best ways forward (1). The workshop on The Potential Use of Non-Invasive Methods in the Safety Ass essment of Cosmetic Products was held in Brussels, Belgium, on 10-12 March 1998, under the co-chairmanship of Michael Palls (ECVAM), Gerald Pierard (t he European Group for Efficacy Measurements on Cosmetics and Other Topical Products [EEMCO]) and Vera Rogiers (EEMCO). The participants included scien tists working in both academia and industry. The current status of clinical and instrumental assessment of the efficacy of cosmetics was reviewed, together with the potential of using non-invasiv e techniques in safety assessment with human volunteers.