N. Macdonald et al., A comparison of national cancer registry and direct follow-up in the ascertainment of ovarian cancer, BR J CANC, 80(11), 1999, pp. 1826-1827
The National Health Service Central Register (NHSCR) and direct follow-up w
ere used to document ovarian and fallopian tube cancers in 22 000 women fro
m 1986 to 1993. Direct follow-up identified 47/49 cases (96%) and the NHSCR
38/49 (78%). NHSCR ascertainment was incomplete and direct follow-up provi
ded additional information. These findings have implications for interpreta
tion of national cancer statistics and for use of the NHSCR in research tri
als.