Postprandial lipoprotein, glucose and insulin responses after two consecutive meals containing rapeseed oil, sunflower oil or palm oil with or without glucose at the first meal

There is increasing evidence that the degree of postprandial lipaemia may b e of importance in the development of atherosclerosis and IHD. Postprandial lipid, lipoprotein, glucose, insulin and non-esterified fatty acid (NEFA) concentrations were investigated in eleven healthy young males after random ized ingestion of meals containing rapeseed oil, sunflower oil or palm oil with or without a glucose drink. On six occasions each subject consumed con secutive meals (separated by 1.75 h) containing 70 g (15 g and 55 g respect ively) of each oil. On one occasion with each oil 50 g glucose was taken wi th the first meal. One fasting! and fifteen postprandial blood samples were taken over 9 h. There were no statistically significant differences in lip oprotein and apolipoprotein responses after rapeseed, sunflower and palm oi ls, whereas insulin responses were lower after sunflower oil than after rap eseed oil (ANOVA, P=0.4). The NEFA and triacylglycerol concentrations at 1. 5 h were reduced when 50 g glucose was taken with the first meal (ANOVA, P< 0.0001 and P<0.05 respectively), regardless of meal fatty acid composition. In conclusion, the consumption of glucose with a mixed meal containing eit her rapeseed, sunflower or palm oil influenced the immediate triacylglycero l and NEFA responses compared with the same meal without glucose, whereas n o significant effect on postprandial lipaemia after a subsequent meal was o bserved. The fatty acid composition of the meal did not significantly affec t the lipid and lipoprotein responses, whereas an effect on insulin respons es was observed.