T. Akihisa et al., Cycloarta-16,24-dien-3 beta-ol: Revised structure of cimicifugenol, a cycloartane triterpenoid, CHEM PHARM, 47(8), 1999, pp. 1157-1160
The structure of a triterpene alcohol isolated from the nonsaponifiable lip
ids of both the root and aerial part extracts of Cimicifuga simplex (Ranunc
ulaceae) was established to be cycloarta-16,24-dien-3 beta-ol (1). Spectral
identity of the 24,25-dihydro derivative (4) of 1 with 24,25-dihydrocimici
fugenol demonstrated that cimicifugenol, previously assigned the erroneous
structure of cycloarta-7,24-dien-3 beta-ol, possesses structure 1.