A new stereoselective approach to the manzamine alkaloids

Authors
Coldham, I Coles, SJ Crapnell, KM Fernandez, JC Haxell, TFN Hursthouse, MB Moseley, JD Treacy, AB
Citation
I. Coldham et al., A new stereoselective approach to the manzamine alkaloids, CHEM COMMUN, (17), 1999, pp. 1757-1758
Citations number
31
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
17
Year of publication
1999
Pages
1757 - 1758
Database
ISI
SICI code
1359-7345(19990907):17<1757:ANSATT>2.0.ZU;2-5
Abstract
The key step in a new, stereoselective approach to the manzamine alkaloids involves an intramolecular azomethine ylide cycloaddition reaction, which f orms rings B and C simultaneously, together with three new chiral centres; this has allowed a rapid access to the core ABC ring system of manzamine A.