A 46-year-old woman with advanced ovarian carcinoma had progressive dyspnea
and was evaluated with ventilation and perfusion lung imaging. A character
istic pattern of multiple branching perfusion defects of a segmental nature
on the perfusion scan suggested tumor microembolism and lymphangitic carci
nomatosis. However, in this case, this pattern was associated with pulmonar
y thromboembolism and was documented by the post mortem examination. Pulmon
ary thromboembolism should be included among the differential diagnoses in
a patient with clinical symptoms and a perfusion scan that reveals multiple
branching perfusion defects.