Feline colonic diseases are less common than diseases of the small bowel bu
t are nevertheless diagnostic and therapeutic challenges. One aspect of dev
eloping a rational approach to diagnosing and treating colonic disease is t
o understand the colon's unique physiologic and functional differences. Lar
ge bowel diarrhea can be acute (present for less than 3 weeks) or chronic.
Acute diarrhea is often associated with dietary disturbances (e.g., dietary
indiscretion, food intolerance) or infectious/inflammatory diseases, inclu
ding parasitic or protozoal infestations. Empiric therapy with antibiotics
or anthelmintics or dietary changes often correct the problem. However, man
y chronic colonic diseases (e.g., inflammatory bowel disease, neoplasia) re
quire lifelong pharmacologic and/or dietary intervention.