Glioblastoma multiforme in a mature ovarian teratoma with recurring brain tumours

Aims: We report a case study to highlight the occurrence of glioblastoma mu ltiforme in an ovarian teratoma. Methods and results: A 10-year-old girl presented with a left frontal lobe primitive neuroectodermal tumour which was successfully treated. After 6 un eventful years, she developed glioblastoma multiforme located posterior to the site of the initial tumour. Six years later, she presented with a matur e cystic teratoma containing glioblastoma multiforme. Conclusions: Glioblastoma in an ovarian teratoma is an exceptional event, w hich might have an initial clinical presentation as a metastatic brain tumo ur. Alternatively, recurring glial tumours may occur in a genetically predi sposed person; the role of radiation and chemotherapy in this context remai ns to be elucidated.