COMPARATIVE-ANALYSIS OF PROTEINS OF PERSI STENT AND ANTIGEN-DEFECTIVESTRAINS OF TICK-BORNE ENCEPHALITIS-VIRUS

Authors
PRESSMAN YK MALENKO GV POGODINA VV MATVEYEVA VA BOCHKOVA NG LEVINA LS
Citation
Yk. Pressman et al., COMPARATIVE-ANALYSIS OF PROTEINS OF PERSI STENT AND ANTIGEN-DEFECTIVESTRAINS OF TICK-BORNE ENCEPHALITIS-VIRUS, Voprosy virusologii, 42(2), 1997, pp. 53-56
Citations number
11
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
42
Issue
2
Year of publication
1997
Pages
53 - 56
Database
ISI
SICI code
0507-4088(1997)42:2<53:COPOPS>2.0.ZU;2-F
Abstract
Structural (E) and three nonstructural (NSI, NS3, and NS5) proteins of persistent and antigen-defective strains of tick-borne encephalitis v irus are compared by immunoblotting with monoclonal antibodies to the corresponding proteins of strain Sofyin. Appreciable phenotypical diff erences were revealed between antigen-defective strains, but no immuno logical modifications as concerns the studied antigenic structures. Th e size of the reference NS3 protein differed from that of the persiste nt virus strains. Similar proteins detected in the antigenic preparati ons of strain Zausaev may have no-table modifications.