STUDY OF THE PHAGOCYTIC-ACTIVITY OF BLOOD POLYMORPHONUCLEAR LEUKOCYTES OF RABBITS AND GUINEA-PIGS UPON CHALLENGE WITH EBOLA-VIRUS

Authors
DADAYEVA AA SIZIKOVA LP BAKULINA LF CHEPURNOV AA
Citation
Aa. Dadayeva et al., STUDY OF THE PHAGOCYTIC-ACTIVITY OF BLOOD POLYMORPHONUCLEAR LEUKOCYTES OF RABBITS AND GUINEA-PIGS UPON CHALLENGE WITH EBOLA-VIRUS, Voprosy virusologii, 42(2), 1997, pp. 56-59
Citations number
20
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
42
Issue
2
Year of publication
1997
Pages
56 - 59
Database
ISI
SICI code
0507-4088(1997)42:2<56:SOTPOB>2.0.ZU;2-4
Abstract
Study of the phagocytic activity of polymorphonuclear leukocytes (PMNL ) of rabbits resistant to Ebola virus and guinea pigs susceptible to i t, repeatedly challenged with live or inactivated Ebola virus in accor dance with the immunization protocols, showed a much higher phagocytic activity in animals resistant to the virus than in those susceptible to if. Such behavior of PMNL in guinea pigs may be explained by the ab sence of the necessary cytokine background activating the neutrophils.