EFFECT OF INACTIVATED EBOLA-VIRUS ON THE COLONY-FORMING ACTIVITY OF HEMATOPOIETIC PRECURSORS IN MAN

Authors
CHEPURNOV AA TYUNNIKOV GI CHERNUKHIN IV
Citation
Aa. Chepurnov et al., EFFECT OF INACTIVATED EBOLA-VIRUS ON THE COLONY-FORMING ACTIVITY OF HEMATOPOIETIC PRECURSORS IN MAN, Voprosy virusologii, 42(2), 1997, pp. 91-92
Citations number
12
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
42
Issue
2
Year of publication
1997
Pages
91 - 92
Database
ISI
SICI code
0507-4088(1997)42:2<91:EOIEOT>2.0.ZU;2-1
Abstract
The effect of Ebola virus antigen on the growth of hemopoietic precurs ors was studied. Incubation of mononuclear cells with the viral antige n led to a dose-dependent decrease of erythroid colony formation but d id not alter the growth of the granulocyto-macrophagal precursors. Hen ce, Ebola virus antigen is capable of directly affecting the hemopoiet ic activity of precursors in man by inhibiting the growth of erythroid colonies.