Aa. Chepurnov et al., EFFECT OF INACTIVATED EBOLA-VIRUS ON THE COLONY-FORMING ACTIVITY OF HEMATOPOIETIC PRECURSORS IN MAN, Voprosy virusologii, 42(2), 1997, pp. 91-92
The effect of Ebola virus antigen on the growth of hemopoietic precurs
ors was studied. Incubation of mononuclear cells with the viral antige
n led to a dose-dependent decrease of erythroid colony formation but d
id not alter the growth of the granulocyto-macrophagal precursors. Hen
ce, Ebola virus antigen is capable of directly affecting the hemopoiet
ic activity of precursors in man by inhibiting the growth of erythroid
colonies.