Treatment of glaucoma, or elevated intraocular pressure (IOP) after penetra
ting keratoplasty (PKP), can be one of the most frustrating ophthalmic prob
lems, particularly as elevated IOP not only may result in visual loss from
optic nerve damage but may compromise the corneal graft endothelium. Furthe
rmore, the treatment itself is prone to being ineffective or may put the pa
tient at increased risk of graft failure.