Lymphocyte nucleus reconstruction via wavelet tomography

A wavelet tomographic algorithm is presented for statistical reconstruction of a lymphocyte nucleus. The investigation is concerned with lymphocyte nu clei of peripheral blood from two groups of patients: those who live in the area affected by the Chernobyl accident and the control group. The purpose of reconstruction is to find the probability density function of radial di stribution of condensed chromatin. The difference between the two test grou ps is seen from considering the results of reconstruction and the wavelet e nergy spectra. The Radon transform is treated here as a singular wavelet tr ansform, which allows us to reconstruct the essential scales from projectio n and to denoise them simultaneously. The algorithm of reconstruction invol ves back projecting and continuous wavelet synthesis with denoising. The us e of a special local filter insures the stability of reconstruction. a 1999 Society of Photo-Optical Instrumentation Engineers. [S1083-3668(99)00603-6 ].