Pseudophakic cystoid macular edema treated with high-dose intravenous methylprednisolone

Purpose: To evaluate the efficacy of high-dose methylprednisolone in the tr eatment of pseudophakic cystoid macular edema (CME). Setting: University-affiliated hospital. Methods: Four patients with pseudophakic CME who reported decreased visual acuities were treated with oral prednisolone (20 mg daily for 5 days), oral acetazolamide (500 mg daily for 5 days), and topical dexamethasone 0.1% an d diclofenac 0.1% (4 times a day for 14 days). The CME did not resolve. Nex t, they were treated with high-dose (1000 mg daily) intravenous methylpredn isolone for 3 days. Results: in 3 of 4 eyes, the CME resolved and visual acuity improved. Conclusion: High-dose methylprednisolone may be effective in the treatment of pseudophakic CME. (C) 1999 ASCRS and ESCRS.