Qualitative and quantitative analysis of new alkyl amide arginine surfactants by high-performance liquid chromatography and capillary electrophoresis

A protocol for the qualitative and quantitative analysis of novel arginine- based cationic surfactants using HPLC and CE was studied and compared. The optimization of the analytical conditions was carried out through a systema tic variation of the experimental parameters such as mobile phase, eluent c onditions, ion pairing and amount of sample for HPLC, and type of buffer, i on strength, type and amount of organic solvent, sample injection time, app lied voltage and column washing and conditioning for CE. (C) 1999 Elsevier Science B.V. All rights reserved.