Staphylococcus aureus isolation from the lesions, the hands, and anterior nares of patients with atopic dermatitis

Staphylococcus aureus colonization is common in atopic dermatitis (AD) and can exacerbate the disease. Some patients with atopic dermatitis may act as a reservoir for S. aureus transmission to others. This study compared S, a ureus colonization in atopic dermatitis patients and their caregivers; with control patients and their caregivers, Quantitative cultures were obtained from the lesions, clinically normal skin, hands, and anterior nares of 100 patients with atopic dermatitis, 100 controls with other cutaneous disorde rs, and 200 caregivers, The AD patients had significantly greater presence of S aureus from lesional and clinically normal skin, as well as the hand. Significantly increased carriage of S, aureus was found in the anterior nar es of caretakers of AD patients compared with control caretakers. Topical c orticosteroid use did not affect recovery. of S. aureus, There was a signif icant correlation between recovery of S, aureus from lesional skin and reco very from the anterior nares and hands. The nares and hands may be importan t reservoirs and vectors for autotransmission of S, aureus to lesional skin and for transmission to patients with AD. (C) 1999 Elsevier Science Inc.