A new sample holder that allows combined microtomy for atomic force microsc
opy (APM) and transmission electron microscopy (TEM) is described. The main
feature of this sample holder is a small central part holding the sample.
This central part fits into the head of an atomic force microscope. AFM mea
surements can be performed with a sample mounted in this central part of th
e sample holder. This makes the alignment of a microtomed built: sample unn
ecessary, and offers the opportunity of an easy and fast combined sample pr
eparation for AFM and TEM.