BACKGROUND: Gynecologists are frequently asked to evaluate patients with vu
lvar lesions. Although the differential diagnosis of a vulvar lesion is var
ied, the main concern is to rule out a vulvar malignancy. Primary vulvar ca
rcinoma is uncommon, and a metastatic cancer from an extragenital site invo
lving the vulva is even more rare.
CASE: A 78-year-old woman with a history of a transitional cell carcinoma (
TCC) of the bladder presented with two painful vulvar lesions, which repres
ented the first manifestation of metastatic disease. This is the fifth repo
rted case of TCC from the bladder with metastases to the vulva.
CONCLUSION: The differential diagnosis of a vulvar lesion, especially in a
woman with a prior history of renal tract malignancy, should include metast
atic lesions.