Comparison of flash lamp pulsed-dye laser (585 nm) and conventional surgery in the delay of random dorsal rat flaps

Citation
M. Cohen et al., Comparison of flash lamp pulsed-dye laser (585 nm) and conventional surgery in the delay of random dorsal rat flaps, LASER SURG, 25(2), 1999, pp. 178-186
Citations number
16
Categorie Soggetti
Surgery
Journal title
LASERS IN SURGERY AND MEDICINE
ISSN journal
01968092 → ACNP
Volume
25
Issue
2
Year of publication
1999
Pages
178 - 186
Database
ISI
SICI code
0196-8092(1999)25:2<178:COFLPL>2.0.ZU;2-W
Abstract
Background and Objective: Delay is a basic surgical technique used by flap surgeons to improve the blood supply to the distal parts of a random skin f lap. The aim of this study was to determine whether a scarless delay can be done by the use of the flash lamp pulsed-dye laser operating at a waveleng th of 585 nm. Study Design/Materials and Methods: The pilot study showed that 6 J/cm(2) h ad a selective photothermolysis effect and therefore was chosen for testing the delay procedure on 15 rats. The percentage of flap necrosis of this gr oup was compared to the results of 15 rats that underwent delay by surgery and 15 rats that were not treated prior to flap surgery (control group). Results: Laser delay of McFarlane flaps resulted in an average of 15.5% sma ller necrotic area compared to the control group (52.7% +/- 14.4% and 68.2% +/- 9.6%, respectively, P < 0.01) and was as effective as surgical delay ( 53.3% +/- 13.6%). Conclusions: The results indicate that the flash lamp pulsed-dye laser oper ating at 585 nm is effective for delaying cutaneous flaps in the rat model. (C) 1999 Wiley-Liss, Inc.