K. Koch et al., Chemometric evaluation of in vitro examination for bioavailability of zincin selected foodstuffs and menus, NAHRUNG, 43(4), 1999, pp. 259-264
Using simulated digestion-juices for extraction of 31 foodstuffs and 4 menu
es, 7 variables were subjected to measuring Various polarographic parameter
s as well as determining antagonists of zinc absorbtion, and were evaluated
by chemometric methods. Correlations between the different vaiables were d
etermined by factor analysis, and 4 factors were extracted. By means of clu
ster analysis it was established whether similarities between the 31 foodst
uffs and 4 menues are existing. The resulting division into groups of bioav
ailability (high, medium, small) was compared with references based on in v
ivo methods. A high agreement was established. The found clusters were char
acterized by discriminance analysis allowing an arrangement of further food
stuffs into different groups of bioavailability.